Export Controls: Pathogens and Toxins
Categories:
Pathogens and Toxins
Department of Commerce dual-use export control-listed pathogens and toxins are listed below. These pathogens and toxins are found on the Commerce Control List (CCL) in Category 1 at ECCNs 1C351 through 1C360. Please note that export controls also apply to genetic elements and genetically modified organisms that contain DNA associated with the pathogenicity of these biological materials. Severe civil and/or criminal penalties apply to international shipments without an export license of ANY export controlled pathogen or genetic material containing the controlled DNA.
You will need to contact Stanford's Export Control Office if your research requires an export controlled pathogen or genetic material containing the controlled DNA to be sent outside of the US so that an export license application can be prepared. Export licenses take 4-6 weeks for approval, so please plan in advance.
Also note that the International Traffic in Arms Regulations (ITAR) controls certain military-related toxins and pathogens at Category XIV of the US Munitions List (USML). The ITAR, which is generally implicated for DoD-funded activity, treats as an USML-controlled defense article any "biological agent or biologically derived substance specifically developed or modified to increase its capability to produce casualties in humans or livestock or to degrade equipment or damage crops." These ITAR controlled biological materials will also require an export license when shipped internationally. Similarly, foreign nationals may not access ITAR-controlled biological materials or their unpublished technical data in the US without an ITAR license.
In the unlikely event that you need access to an ITAR controlled biological material or its technical data at Stanford, you must first contact Stanford's Export Control Office as required by the RPH Chapter: Export Control before receipt. The Export Control Office will review the proposed receipt to ensure export compliance and consistency with Stanford's Openness in Research and Nondiscrimination in Research Agreement policies.
A
African horse sickness virus
African swine fever virus
Andean potato latent virus (Potato Andean latent tymovirus)
Andes virus
Avian Influenza identified as having high pathogenicity *
Toxins
Abrin
Aflatoxins
B
Bacillus anthracis
Blue Tongue virus
Brucella abortus
Brucella melitensis
Brucella suis
Burkholderia mallei (Pseudomonas mallei)
Burkholderia pseudomallei
Toxins
Botulinum toxins
C
Chapare virus
Chikungunya virus
Chlamydophilia psittaci (Chlamydia psittaci)
Choclo virus
Clavibacter michiganensis subspecies sepedonicus (Corynebacterium sepedonicum)
Clostridium Argentinense, botulinum neurotoxin producing strains (Clostricium botulinum Type G)
Clostridium baratii, botulinum neurotoxin producing strains
Clostridium botulinum
Clostridium butyricum
Clostridium perfringens (epsilon toxin producing type)
Coccidioides immitis
Coccidioides posadasii
Cochliobolus miyabeanus (Helminthosporium oryzae)
Colletotrichum kahawae (Colleototrichum coffeanum var. virulans)
Congo-Crimean haemorrhagic fever virus
Coxiella burnetii
Toxins
Cholera toxin
Clostridium perfringens toxin
Conotoxins
D
Dengue fever virus
Dobrava-Belgrade virus
Toxins
Diacetoxyscirpenol toxin
E
Eastern equine encephalitis virus
Ebola virus
F
Foot and Mouth Disease virus
Francisella tularensis
G
Goat Pox virus
Guanarito virus
H
Hantaan virus
Hendra virus
Toxins
HT-2 toxin
I
none listed
J
Japanese Encephalitis virus
Junin virus
K
Kyasanur Forest virus
L
Laguna Negra virus
Lassa fever virus
Louping Ill virus
Lujo virus
Lumpy Skin Disease virus
Lymphocytic choriomeningitis virus
Lyssa virus
M
Machupo virus
Magnaporthea grisea (Pyricularia oryzae)
Marburg virus
Microcyclus ulei (Dothidella ulei)
Monkeypox virus
Murray Valley encephalitis virus
Mycoplasma capricolum subspecies capripneumonaie (strain F38)
Mycoplasma mycoides subspecies mycoides small colony (contagious bovine pleuroneumonia)
Toxins
Microcystin (Cyanginosin)
Modeccin toxin
N
Newcastle disease virus
Nipah virus
O
Omsk haemorrhagic fefer virus
Oropouche Virus
P
Peronosclerospora philippinensis (Peronosclerospora sacchari)
Peste des Petitis Ruminants virus
Phoma glycinicola (Pyrenochaeta glycines)
Porcine enterovirus type 9 (swine vesicular disease virus)
Porcine herpes virus (Aujeszky's disease)
Potato spindle tuber viroid
Powassan virus
Puccinia Graminis (Puccinia graminis f. sp. Tritici)
Puccinia striiformis (Puccinia glumarum)
Q
none listed
R
Ralstonia solanacearum Race 3, biovar 2
Rathayibacter toxicus
Reconstructed replication competent forms of the 1918 pandemic influenza virus containing any portion of the coding regions of all eight gene segment
Rickettsia prowazekii
Rift Valley fever virus
Rinderpest virus
Rocio virus
Toxins
Ricin
S
Sabia virus
Salmonella typhi
SARS-associated coronavirus (SARS-CoV)
Sclerophthora rayssiae var.zeae
Seoul virus
Sheep Pox virus
Shigella dysenteriae
Sin Nombre virus
St. Louis encephalitis
Swine Fever virus (Hog cholera virus)
Synchytrium endobioticum
Toxins
Saxitoxin
Shiga toxin
Shiga toxin producing Escherichia coli (STEC) of serogroups 026, 045, 0103, 0104, 0111, 0121, 0145, 0157, and other shiga toxin producing serogoups (EGEC or VTEC)
Staphylococcus aureus enterotoxins, hemolysin alpha toxin, and toxic shock syndrome toxin (Staphylococcus enterotoxin F)
T
Teschen Disease virus
Thecaphora solani
Tick-borne encephalitis virus (Far Eastern Subtype)
Tick-borne encephalitis virus (Siberian Subtype)
Tilletia indica
Toxins
T-2 toxin
Tetrodotoxin
U
none listed
V
Variola virus
Venezuelan Equine Encephalitis virus
Vesicular stomatitis virus
Vibrio cholerae
Toxins
Verotoxin and other Shiga-like ribosome inactivating proteins
Viscum Album Lectin 1 (Viscumin)
Volkensin toxin
W, X, Y, Z
Western Equine Encephalitis virus
Xanthmonas alibilineans
Xanthmonas axonopodis pv. Citri (Xanthomonas campestris pv. citri)
Xanthomonas oryzae pv. Oryzae (Pseudomonas campestris pv. Oryzae)
Yellow fever virus
Yersinia pestis
* AI viruses that have an intravenous pathogenicity index in 6-week-old chickens greater than 1.2; AI viruses that cause at least 75% mortality in 4 to 8 week old chickens infected intravenously; AI viruses of the H5 or H7 should be submitted to further testing